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First, although copper is essential for autophagy, high concentrations of copper might induce mitophagy by generating mtROS [151,152,153], altering mitochondrial membrane potential or inhibiting mTOR activity [154, 155]

Paiva I et al 2022 Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription

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A doublet occurs when there are twin branches that come off together instead of one, which are exactly symmetrical, in each of the lower locations that can be seen. In a study of ASD children in Sweden, airway symptoms of wheezing and physician-diagnosed asthma in the baseline investigation in infants and toddlers were associated with ASD 5 years later